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EPDC outgrowth inhibition may result in marked defects in the fibrous annulus with persistence of large APs, which results in ventricular preexcitation on ECG. 心外膜起源细胞生长抑制，可能导致多数房室旁道持续发生的纤维环的显著缺陷，其引起了心电图上心室的提前刺激。