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Objection:To separate and identify the primary impurities in sophoridine. 目的:对槐定碱中主要微量杂质分离和鉴定。
Objective To optimize the preparation process for preparing lung-targeted sophoridine(microsphere)(SR-MS). 目的优选肺靶向槐定碱白蛋白微球的制备工艺。
Abstract:Objective To observe whether Sophoridine Hydrochloride for Injection has vascular stimulation,hemolyzation,agglutination and sensitization. 妇科恶性肿瘤是最常见的肿瘤之一,它严重影响了妇女的生活质量和生命时间。
ResultsIt showed that the Sophoridine Hydrochloride for Injection had no vascular irritation and injury effect on rabbit vascular endothelial cell. 与同类产品比较,可明显降低患者治疗痛苦和辅助治疗的经济负担。
Oxymartrine and low dose group of Sophoridine could significantly prolong the latencies of epileptic seizure, and reduced seizure degree compared with penicillin group. 结果与致痫组相比氧化苦参碱低、高剂量组和槐定碱低剂量组均能不同程度地延长痫性发作潜伏期,并且降低痫性发作程度;