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Objective To isolate fungi from sea sediment and sea water samples collected from the neritic environment in Qingdao, screen their antitumor activity and study on their fermentation condition. 目的对青岛海域海水、海泥样品进行真菌选择性分离培养，并对其发酵物进行抗肿瘤活性筛选及活性菌株发酵条件的研究。