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These results suggest that ASPM gene is involved in cell mitosis, proliferation and differentiation. 这些结果显示ASPM基因与细胞分裂,细胞增殖以及细胞分化有著相关性。
By differential display method, we identified the human ASPM gene that was frequently overexpresses in HCC. 利用基因分示法,我们发现人类ASPM基因在肝细胞癌中常会有过量的表现。
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ASPM gene was also expressed in multiple fetal tissues and several cancer cell lines, but not adult tissues. ASPM基因同时也表现在多个胎儿器官与数种癌症细胞株之中,但在成人器官中则表现量很低。
The homozygous mutations of ASPM gene are the most common cause of MCPH and lead to microcephaly and mental retardation. ASPM基因的同型合子突变是造成MCPH最常见的原因,会造成病患的小脑症且心智发育迟缓。